FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Siren, L.L.C.
2. Date of Event Requiring Statement (Month/Day/Year)
07/25/2024
3. Issuer Name and Ticker or Trading Symbol
Scholar Rock Holding Corp [SRRK]
(Last)
(First)
(Middle)
C/O THE INVUS GROUP, LLC, 750 LEXINGTON AVENUE 30TH FLOOR
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed (Month/Day/Year)
(Street)

NEW YORK, NY 10022
6. Individual or Joint/Group Filing (Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 11,259,438
D (1) (2)
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Warrant (right to buy) 06/22/2022 12/31/2025 Common Stock 1,575,008 $ 7.35 D (1) (2)  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Siren, L.L.C.
C/O THE INVUS GROUP, LLC
750 LEXINGTON AVENUE 30TH FLOOR
NEW YORK, NY 10022
    X    
Invus Global Management, LLC
750 LEXINGTON AVENUE 30TH FLOOR
NEW YORK, NY 10022
    X    
DEBBANE RAYMOND
750 LEXINGTON AVENUE 30TH FLOOR
NEW YORK, NY 10022
    X    

Signatures

INVUS GLOBAL MANAGEMENT, LLC, By: /s/ Raymond Debbane, Name: Raymond Debbane, Title: President 07/29/2024
**Signature of Reporting Person Date

SIREN, L.L.C., By: /s/ Raymond Debbane, Name: Raymond Debbane, Title: President 07/29/2024
**Signature of Reporting Person Date

RAYMOND DEBBANE, By: /s/ Raymond Debbane 07/29/2024
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The Common Stock and Warrants are held directly by Invus Public Equities, L.P. The general partner of Invus Public Equities, L.P. is Invus Public Equities Advisors, LLC. On July 25, 2024, in connection with a reorganization, Invus Global Management, LLC replaced the Geneva branch of Artal International S.C.A. as the managing member of Invus Public Equities Advisors, LLC. As a result of the reorganization, Invus Global Management, LLC as the managing member of Invus Public Equities Advisors, LLC, Siren, L.L.C. as the managing member of Invus Global Management, LLC and Mr. Raymond Debbane as the managing member of Siren, L.L.C. may now be deemed to beneficially own the securities beneficially owned by Invus Public Equities Advisors, LLC.
(2) Each of the reporting persons (other than to the extent it directly holds securities reported herein), disclaims beneficial ownership of the securities held by the other reporting persons, except to the extent of such reporting person's pecuniary interest therein, and, pursuant to Rule 16a-1(a)(4) under the Exchange Act, each of the reporting persons (other than to the extent it directly holds securities reported herein) states that the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 of the Exchange Act or for any other purpose.

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