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                                May 15, 2024

       Benjamin Stilwill
       Chief Executive Officer
       Streamline Health Solutions, Inc.
       2400 Old Milton Pkwy., Box 1353
       Alpharetta, GA 30009

                                                        Re: Streamline Health 
Solutions, Inc.
                                                            Registration 
Statement on Form S-3
                                                            Filed May 7, 2024
                                                            File No. 333-279190

       Dear Benjamin Stilwill:

              We have conducted a limited review of your registration statement 
and have the
       following comment.

              Please respond to this letter by amending your registration 
statement and providing the
       requested information. If you do not believe our comment applies to your 
facts and
       circumstances or do not believe an amendment is appropriate, please tell 
us why in your
       response.

              After reviewing any amendment to your registration statement and 
the information you
       provide in response to this letter, we may have additional comments.

       Form S-3 filed May 7, 2024

       Selling Securityholders, page 8

   1.                                                   Please disclose the 
natural person or persons who exercise sole or shared voting and/or
                                                        dispositive powers with 
respect to the shares held by Resilient Holding LLC and
                                                        Tammaro Realty LLC. 
Also, please identify any selling stockholder that is a registered
                                                        broker-dealer or an 
affiliate of a broker-dealer. Please note that a registration statement
                                                        registering the resale 
of shares being offered by a broker-dealer must identify the broker-
                                                        dealer as an 
underwriter if the shares were not issued as underwriting compensation. For a
                                                        selling stockholder 
that is an affiliate of a broker-dealer, your prospectus must state, if
                                                        true, that: (1) the 
seller purchased the securities in the ordinary course of business; and (2)
                                                        at the time of purchase 
of the securities you are registering for resale, the seller had no
                                                        agreements or 
understandings, directly or indirectly, with any person, to distribute the
                                                        securities. If you are 
unable to make these statements in the prospectus, please disclose
 Benjamin Stilwill
Streamline Health Solutions, Inc.
May 15, 2024
Page 2
         that the selling stockholder is an underwriter.
        We remind you that the company and its management are responsible for 
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action 
or absence of
action by the staff.

        Refer to Rule 461 regarding requests for acceleration. Please allow 
adequate time for us
to review any amendment prior to the requested effective date of the 
registration statement.

       Please contact Marion Graham at 202-551-6521 or Matthew Crispino at 
202-551-3456
with any other questions.



FirstName LastNameBenjamin Stilwill                         Sincerely,
Comapany NameStreamline Health Solutions, Inc.
                                                            Division of 
Corporation Finance
May 15, 2024 Page 2                                         Office of 
Technology
FirstName LastName