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                             April 4, 2024

       Mark Lappe
       Chief Executive Officer
       Inhibrx Biosciences, Inc.
       11025 N. Torrey Pines Road, Suite 140
       La Jolla, CA 92037

                                                        Re: Inhibrx 
Biosciences, Inc.
                                                            Amendment No. 1 to 
Draft Registration Statement on Form 10
                                                            Submitted on March 
4, 2024
                                                            CIK No. 0002007919

       Dear Mark Lappe:

            We have reviewed your amended draft registration statement and have 
the following
       comments.

              Please respond to this letter by providing the requested 
information and either submitting
       an amended draft registration statement or publicly filing your 
registration statement on
       EDGAR. If you do not believe a comment applies to your facts and 
circumstances or do not
       believe an amendment is appropriate, please tell us why in your 
response.

               After reviewing the information you provide in response to this 
letter and your amended
       draft registration statement or filed registration statement, we may 
have additional
       comments. Unless we note otherwise, any references to prior comments are 
to comments in our
       February 29, 2024 letter.

       Amendment No. 1 to Draft Registration Statement on Form 10

       Questions and Answers about the Separation and Distribution
       What conditions must be satisfied to complete the Spin-Off?, page xi

   1.                                                   We note your response 
to comment 1. Please explain how you can procede with the
                                                        proposed transactions 
if there is a stop order, injunction or law preventing the
                                                        consummation of the 
Separation, Distribution or Merger or if the effectiveness of the
                                                        registration statement 
is waived.
       Risk Factors
       Our therapeutic candidates may cause undesirable side effects that could 
delay or prevent their
       marketing..., page 16
 Mark Lappe
FirstName   LastNameMark
Inhibrx Biosciences,  Inc. Lappe
Comapany
April       NameInhibrx Biosciences, Inc.
       4, 2024
April 24, 2024 Page 2
Page
FirstName LastName

2.       We note your response to comment 8 and re-issue in part. Please 
identify all serious
         adverse events, not just the most common ones, in your risk factor 
discussion and on
         pages 88-89 and specify the number of occurrences.
Note 1: Basis of Presentation, page 134

3.       You describe the sale of the RemainCo Business as a distribution of 
nonmonetary assets
         to the owners in a spin-off, which appears to differ from related 
disclosure as the sale the
         RemainCo Business to Sanofi in exchange for its purchase of all 
outstanding shares of
         Inhibrx Inc. for cash and CVRs. Please reconcile this apparent 
inconsistency.
Note 2: Separation of the RemainCo Business, page 135

4.       Please explain the basis for your allocation of research and 
development expenses of
         $54.69 million to RemainCo, when your discussion on page 144 appears 
to indicate that
         increases in contract manufacturing and clinical trial expenses 
totaling $63.9 million
         related to INBRX-101. Include an estimate of your external and 
internal expenses for
         2023 that related to development of INBRX-101. Revise your pro forma 
presentation
         accordingly.
Notes to Unaudited Pro Forma Condensed Consolidated Financial Statements
Note 3: Transaction Accounting Adjustment, page 137

5.       Please address the following regarding the tax effects of the proposed 
transaction:
             You state for that the applicable tax rates for Transaction 
Accounting Adjustments as
             well as Autonomous Entity Adjustments    could be impacted (either 
higher or lower)
             depending on certain factors subsequent to the Separation and 
Distribution including
             the legal entity structure implemented and may be materially 
different from the pro
             forma results.    Please provide a more informative description of 
these factors with
             reference to other sections of your filing as applicable, and 
quantify the reasonably
             likely impact on pro forma results. To the extent a range of 
results exists, disclose
             that range of likely outcomes.
             Provide updates to this disclosure as additional information about 
the tax implications
             becomes available.
             Provide a detailed explanation supporting your assertion on page 
63 that    the Spin-
             Off in combination with the Merger is more tax advantageous to 
RemainCo   s
             stockholders as compared to an asset sale involving INBRX-101.    
Revise your
             disclosures accordingly.
Management's Discussion and Analysis of Financial Condition and Results of 
Operations, page
139

6.       In your response to prior comment 13, you state that you track some 
but not all of your
         research and development expenses. As previously requested, to the 
extent you track your
         research and development expenses on a program-by-program basis, 
revise to provide a
 Mark Lappe
Inhibrx Biosciences, Inc.
April 4, 2024
Page 3
       breakout of those amounts by program. Disclose the context of what type 
of expenses are
       tracked separately by program versus those that are not tracked.
Index to Consolidated Financial Statements, page F-1

7.     We note your response to prior comment 12. Please revise your Form 10 to 
provide carve
       out financial statements for Inhibrx Biosciences, Inc. on a supplemental 
basis. It appears
       that carve out financial statements would be required in your Form 10 as 
well your future
       '34 Act filings until the period in which the sale of Remainco to 
Aventis is completed.
Notes to Consolidated Financial Statements
1. Organization and Summary of Significant Accounting Policies
Collaborative Research, Development and License Agreements, page F-13

8.     In the response to prior comment 14, you state that no work has been 
performed under the
       Transcenta agreements since 2019 and that none is planned in future 
periods, while
       information on pages 83, 93 and 140 as well as related Exhibits in the 
2023 Form 10-K for
       Inhibrx Inc. appear to indicate that this collaboration as well as the 
Elpiscience
       collaboration, are critical to the future development and commercial 
prospects of INBRX-
       109 and INBRX-106 that will be your primary development projects 
following the
       planned Separation and Distribution. Revise your disclosures throughout 
your document
       to reconcile this apparent inconsistency. As part of your response, 
please explain the
       strategy and expected timing for your development and commercialization 
of these two
       products in the United States, China and other global markets and how 
you expect these
       two collaborative arrangements to facilitate your planned business 
activities in China,
       Hong Kong, Macau and Taiwan. In addition, provide a summary of key terms 
governing
       each collaboration.
       Please contact Franklin Wyman at 202-551-3660 or Kevin Vaughn at 
202-551-3494 if
you have questions regarding comments on the financial statements and related 
matters. Please
contact Jimmy McNamara at 202-551-7349 or Suzanne Hayes at 202-551-3675 with 
any other
questions.



                                                            Sincerely,
FirstName LastNameMark Lappe
                                                            Division of 
Corporation Finance
Comapany NameInhibrx Biosciences, Inc.
                                                            Office of Life 
Sciences
April 4, 2024 Page 3
cc:       Brian M. Janson
FirstName LastName