FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
ALEXANDRIA REAL ESTATE EQUITIES, INC.
  2. Issuer Name and Ticker or Trading Symbol
Applied Therapeutics, Inc. [APLT] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
26 NORTH EUCLID AVENUE		 3. Date of Earliest Transaction (Month/Day/Year)
06/04/2024
(Street)

PASADENA, CA 91101		 4. If Amendment, Date Original Filed (Month/Day/Year)
 6. Individual or Joint/Group Filing (Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4) 		7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/04/2024   S   150,000 D $ 4.21 (1) 6,005,077 I By subsidiary (2)
Common Stock 06/05/2024   S   150,000 D $ 4.24 (3) 5,855,077 I By subsidiary (2)
Common Stock               203,977 I By subsidiary (4)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5) 		6. Date Exercisable and Expiration Date
(Month/Day/Year) 		7. Title and Amount of Underlying Securities
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4) 		10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4) 		11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
ALEXANDRIA REAL ESTATE EQUITIES, INC.
26 NORTH EUCLID AVENUE
PASADENA, CA 91101		     X    
Alexandria Venture Investments, LLC
26 NORTH EUCLID AVENUE
PASADENA, CA 91101		     X    
Alexandria Equities No. 7, LLC
26 NORTH EUCLID AVENUE
PASADENA, CA 91101		     X    

Signatures

 ALEXANDRIA REAL ESTATE EQUITIES, INC., By: /s/ Marc E. Binda, Chief Financial Officer and Treasurer   06/06/2024
**Signature of Reporting Person Date

 ALEXANDRIA EQUITIES NO. 7, LLC By: ARE-Special Services, LLC, managing member By: AREE, L.P., managing member By: ARE-QRS CORP., general partner By: Alexandria Real Estate Equities, Inc. By: /s/ Marc E. Binda, Chief Financial Officer and Treasurer   06/06/2024
**Signature of Reporting Person Date

 ALEXANDRIA VENTURE INVESTMENTS, LLC., By: Alexandria Real Estate Equities, Inc., managing member By: /s/ Marc E. Binda, Chief Financial Officer and Treasurer   06/06/2024
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The price reported in Column 4 is a weighted average price. The shares were sold at prices ranging from $4.12 to $4.32. The reporting person will provide upon request to the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.
(2) These securities are held directly by Alexandria Venture Investments, LLC, an affiliate of Alexandria Equities No. 7, LLC ("AE7"), and a wholly owned subsidiary of Alexandria Real Estate Equities, Inc.
(3) The price reported in Column 4 is a weighted average price. The shares were sold at prices ranging from $4.10 to $4.40. The reporting person will provide upon request to the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.
(4) These securities are held directly by AE7, a wholly owned subsidiary of Alexandria Real Estate Equities, Inc.

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