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                          April 24, 2024

       J. Scott Wolchko
       Chief Executive Officer
       Fate Therapeutics, Inc.
       12278 Scripps Summit Dr.
       San Diego, CA 92131

                                                        Re: Fate Therapeutics, 
Inc.
                                                            Registration 
Statement on Form S-3
                                                            Filed April 18, 
2024
                                                            File No. 333-278792

       Dear J. Scott Wolchko:

              This is to advise you that we have not reviewed and will not 
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for 
acceleration. We remind you
       that the company and its management are responsible for the accuracy and 
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of 
action by the staff.

                                                        Please contact Lauren 
Hamill at 303-844-1008 with any questions.



                                                                                
                          Sincerely,

                                                                                
                          Division of Corporation Finance
                                                                                
                          Office of Life Sciences
       cc:                                              Natalie Martirossian