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                               July 7, 2023

       Cary Claiborne
       President and Chief Executive Officer
       Adial Pharmaceuticals, Inc.
       1180 Seminole Trail, Suite 495
       Charlottesville, VA 22901

                                                        Re: Adial 
Pharmaceuticals, Inc.
                                                            Registration 
Statement on Form S-1
                                                            Filed June 23, 2023
                                                            File No. 333-272846

       Dear Cary Claiborne:

              We have limited our review of your registration statement to 
those issues we have
       addressed in our comments. In some of our comments, we may ask you to 
provide us with
       information so we may better understand your disclosure.

              Please respond to this letter by amending your registration 
statement and providing the
       requested information. If you do not believe our comments apply to your 
facts and
       circumstances or do not believe an amendment is appropriate, please tell 
us why in your
       response.

              After reviewing any amendment to your registration statement and 
the information you
       provide in response to these comments, we may have additional comments.

       Registration Statement on Form S-1 filed June 23, 2023

       Cover Page

   1.                                                   We note that you are 
seeking to register 10,199,620 shares of common stock for resale,
                                                        but you disclose on 
page 4 that you only may issue 5,916,575 shares to Alumni Capital
                                                        under the Purchase 
Agreement before obtaining shareholder approval and you disclose on
                                                        page 7 that "only 
1,541,370 shares of common stock remain issuable at this time." More
                                                        specifically, we note 
that all of the common shares you are seeking to register will not be
                                                        duly authorized at the 
time of registration. Please revise your registration statement so that
                                                        the volume of common 
shares registered does not exceed the number of common shares
                                                        that remain available 
for issuance or otherwise advise.
 Cary Claiborne
FirstName   LastNameCary
Adial Pharmaceuticals, Inc.Claiborne
Comapany
July 7, 2023NameAdial Pharmaceuticals, Inc.
July 7,2 2023 Page 2
Page
FirstName LastName
The Alumni Capital Transaction, page 4

2.       We note your disclosure that under your Purchase Agreement with Alumni 
Capital dated
         May 31, 2023, "[u]nder the applicable rules of the Nasdaq, in no event 
may [you] issue
         more than 5,916,575 Shares... unless [you] obtain stockholder approval 
to issue shares of
         Common Stock in excess of the Exchange Cap, provided further that the 
Exchange Cap
         does not apply to the extent the purchase price is equal to or exceeds 
the Minimum Price
         (as defined in the Purchase Agreement)." Please revise your disclosure 
to disclose the
         "Minimum Price" or otherwise advise.
Exhibits

3.       Please revise the legal opinion filed as Exhibit 5.1. The opinion 
should not assume
         material facts underlying the opinion. In this regard, we note that 
the opinion assumes that
            there will be sufficient shares of Common Stock authorized but 
unissued under the
         Certificate of Incorporation and not otherwise reserved for issuance.  
  However, this
         assumption goes to whether the shares will be validly issued. See Item 
II.B.3.a. of Staff
         Legal Bulletin No. 19.
        We remind you that the company and its management are responsible for 
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action 
or absence of
action by the staff.

       Refer to Rules 460 and 461 regarding requests for acceleration. Please 
allow adequate
time for us to review any amendment prior to the requested effective date of 
the registration
statement.

       Please contact Cindy Polynice at 202-551-8707 or Jason Drory at 
202-551-8342 with any
other questions.



                                                               Sincerely,

                                                               Division of 
Corporation Finance
                                                               Office of Life 
Sciences
cc:      Patrick Egan, Esq.