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                                 UNITED STATES                                  
                       SECURITIES AND EXCHANGE COMMISSION                       
                             Washington, D.C. 20549                             

                                  SCHEDULE 13G                                  


                   Under the Securities Exchange Act of 1934                    
                                 (Amendment No.                                 
                                      N/A                                       
                                       )*                                       

                            Jounce Therapeutics Inc                             
                                                                                
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                                (Name of Issuer)                                
                                                                                
                                  Common Stock                                  
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                         (Title of Class of Securities)                         
                                                                                
                                   4811161011                                   
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                                 (CUSIP Number)                                 
                                                                                
                               December 31, 2022                                
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            (Date of Event Which Requires Filing of this Statement)             

Check the appropriate box to designate the rule pursuant to which this 
Schedule is filed:

⌧ Rule 13d-1(b)

□ Rule 13d-1(c)

□ Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting 
person's initial filing on this form with respect to the subject class of 
securities, and for any subsequent amendment containing information which 
would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be 
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange 
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of 
the Act but shall be subject to all other provisions of the Act (however, see 
the Notes).

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CUSIP No. 4811161011      



                                                                                                                                   
          1                                  NAMES OF REPORTING PERSONS                                                            
                                             I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)                           
                       BANK OF AMERICA CORPORATION                                                             
                       56-0906609                                                                              
                                                                                                                                   
2                                            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)                   
                                                                                                                                   
                       (a)   □                                                                            
                       (b)   ⌧                                                                            
                                                                                                                                   
3                                            SEC USE ONLY                                                                          
                                                                                                               
                                                                                                               
                                                                                                                                   
4                                            CITIZENSHIP OR PLACE OF ORGANIZATION                                                  
                                                                                                               
                       Delaware                                                                                
                                                                                                                                   
NUMBER OF SHARES BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:   5                                         SOLE VOTING POWER  
                                            
                       0                    
                                                                     
6                                            SHARED VOTING POWER     
                                            
                       3,276,699            
                                                                     
7                                            SOLE DISPOSITIVE POWER  
                                            
                       0                    
                                                                     
8                                            SHARED DISPOSITIVE POWER
                                            
                       3,276,699            
                                                                                                                                   
9                                            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON                          
                                                                                                               
                       3,276,699                                                                               
                                                                                                                                   
10                                           CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)   
                                                                                                               
                       □                                                                                  
                                                                                                                                   
11                                           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                                     
                                                                                                               
                       6.3 %                                                                                   
                                                                                                                                   
12                                           TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)                                           
                                                                                                               
                       HC                                                                                      
                                                                                                                                   
                                             FOOTNOTES                                                                             
                                                                                                               
                                                                                                               


                                                                                
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Item 1.


 (a) Name of Issuer


  Jounce Therapeutics Inc



 (b) Address of Issuer's Principal Executive Offices


  780 MEMORIAL DRIVE 
  CAMBRIDGE, MA 02139


Item 2.


 (a) Name of Person Filing


  BANK OF AMERICA CORPORATION



 (b) Address of Principal Business Office or, if none, Residence


  BANK OF AMERICA CORPORATE CENTER
  100 N TRYON ST                  
  CHARLOTTE, NC 28255             



 (c) Citizenship


  Delaware



 (d) Title of Class of Securities


  Common Stock



 (e) CUSIP Number


  4811161011




Item 3. If this statement is filed pursuant to (s)(s)240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:



 (a) □ Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).



 (b) □ Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).



 (c) □ Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).



 (d) □ Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8).



 (e) □ An investment adviser in accordance with (s)240.13d-1(b)(1)(ii)(E);



 (f) □ An employee benefit plan or endowment fund in accordance with (s)240.13d-1(b)(1)(ii)(F);



 (g) ⌧ A parent holding company or control person in accordance with (s) 240.13d-1(b)(1)(ii)(G);



 (h) □ A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);



 (i) □ A church plan that is excluded from the definition of an investment company    
            under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);



 (j) □ A non-U.S. institution in accordance with (s) 240.13d-1(b)(1)(ii)(J).



 (k) □ A group, in accordance with (s) 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution
            in accordance with (s) 240.13d-1(b)(1)(ii)(J), please specify the type of institution:     




                                                                                
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Item 4. Ownership.


Provide the following information regarding the aggregate number and 
percentage of the class of securities of the issuer identified in Item 1.



 (a) Amount beneficially owned: 3,276,699



 (b) Percent of class: 6.3 %



 (c) Number of shares as to which the person has:



 (i) Sole power to vote or to direct the vote: 0



 (ii) Shared power to vote or to direct the vote: 3,276,699



 (iii) Sole power to dispose or to direct the disposition of: 0



 (iv) Shared power to dispose or to direct the disposition of: 3,276,699



Item 5. Ownership of Five Percent or Less of a Class


If this statement is being filed to report the fact that as of the date hereof 
the reporting person has ceased to be the beneficial owner of more than five 
percent of the class of securities, check the following □.

Not Applicable


Item 6. Ownership of More than Five Percent on Behalf of Another Person.


Not Applicable


Item 7. Identification and Classification of the Subsidiary Which Acquired
        the Security Being Reported on By the Parent Holding Company      


This statement on Schedule 13G is being filed by Bank of America Corporation 
on behalf of itself and its wholly owned subsidiaries Bank of America N.A. and 
BofA Securities, Inc.


Item 8. Identification and Classification of Members of the Group


Not Applicable


Item 9. Notice of Dissolution of Group


Not Applicable


                                                                                
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Item 10. Certification                                                         
                                                                               
         By signing below I certify that, to the best of my knowledge and      
         belief, the securities referred to above were acquired and are        
         held in the ordinary course of business and were not acquired and     
         are not held for the purpose of or with the effect of changing or     
         influencing the control of the issuer of the securities and were not  
         acquired and are not held in connection with or as a participant      
         in any transaction having that purpose or effect, other than          
         activities solely in connection with a nomination under (s)240.14a-11.

                                                                                


                                   SIGNATURE                                    

After reasonable inquiry and to the best of my knowledge and belief, I certify 
that the information set forth in this statement is true, complete and correct.




                        BANK OF AMERICA CORPORATION      
                                                         
Date: February 10, 2023 By: /s/  Andres Ortiz            
                            Andres Ortiz                 
                            Title:  Authorized Signatory 
                                                         



Footnotes: 


Attention: Intentional misstatements or omissions of fact constitute Federal criminal violations (See 18 U.S.C. 1001)



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BANK OF AMERICA CORPORATION LIMITED POWER OF ATTORNEY

BANK OF AMERICA CORPORATION, a Delaware corporation (the "Corporation"), does 
hereby make, constitute, and appoint each of Kelvin Kwok, Tolu Tade, Andres 
Ortiz Custodio, Frank Lui, James Todd, Zainab Tarteel, Hannah Chae and Monica 
Yako as an attorney-in-fact for the Corporation acting for the Corporation and 
in the Corporation's name, place and stead, for the Corporation's use and 
benefit, to bind the Corporation by their execution of those agreements, forms 
and documents related specifically to Section 13 and Section 16 of the 
Securities Exchange Act of 1934, and other large shareholder and short 
position regulatory reporting requirements in other jurisdictions.
Any documents executed by an attorney-in-fact in accordance with this Limited 
Power of Attorney shall fully bind and commit the Corporation and all other 
parties to such documents may rely upon the execution thereof by the 
attorney-in fact as if executed by the Corporation and as the true and lawful 
act of the Corporation.
This Limited Power of Attorney shall automatically terminate as to the 
authority of Kelvin Kwok, Tolu Tade, Andres Ortiz Custodio, Frank Lui, James 
Todd, Zainab Tarteel, Hannah Chae and Monica Yako upon the earlier of the date 
period of 12 months from the date hereof or the attorney-in-fact's resignation 
or termination from or transfer out of the Compliance and Operational Risk 
Department; however, any such resignation, termination or transfer shall have 
no impact on any documents or instruments executed by any attorney-in-fact 
named above for the Corporation prior to such resignation, termination or 
transfer.
This Limited Power of Attorney shall revoke the Limited Power of Attorney 
executed by the Corporation on July 9, 2021; however, such revocation shall 
have no impact on any actions taken pursuant to that Power of Attorney.
IN WITNESS WHEREOF, this Power of Attorney has been executed and delivered by 
the Corporation to the Attorney-in-Fact on this 4th day of May, 2022.



BANK OF AMERICA CORPORATION


By:Allison L. Gilliam

Allison L. Gilliam
Senior Vice President and Assistant Secretary