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                              October 27, 2022

       Sizhen Wang
       Chief Executive Officer
       Genetron Holdings Limited
       1-2/F, Building 11, Zone 1
       No. 8 Life Science Parkway
       Changping District, Beijing, 102206
       People   s Republic of China

                                                        Re: Genetron Holdings 
Limited
                                                            Annual Report on 
Form 20-F
                                                            Response dated 
September 30, 2022
                                                            File No. 001-39328

       Dear Sizhen Wang:

               We have reviewed your September 30, 2022 response to our comment 
letter and have the
       following comment. In our comment, we may ask you to provide us with 
information so we may
       better understand your disclosure.

              Please respond to this comment within ten business days by 
providing the requested
       information or advise us as soon as possible when you will respond. If 
you do not believe our
       comment applies to your facts and circumstances, please tell us why in 
your response.

             After reviewing your response to this comment, we may have 
additional
       comments. Unless we note otherwise, our references to prior comments are 
to comments in our
       August 16, 2022 letter.

       Annual Report on Form 20-F

       Introduction, page iii

   1.                                                   We note your response 
to prior comment 1. Please ensure that your disclosure in future
                                                        reports clarifies that 
the legal and operation risks associated with operating in China also
                                                        apply to operations in 
Hong Kong and/or Macau. To the extent you have operations in
                                                        Hong Kong or Macau, 
please also ensure that you provide additional disclosure related to
                                                        the enforceability of 
civil liabilities in these jurisdictions.

              You may contact Ibolya Ignat at 202-551-3636 or Angela Connell at 
202-551-3426 if you
       have questions regarding comments on the financial statements and 
related matters. Please
 Sizhen Wang
Genetron Holdings Limited
October 27, 2022
Page 2

contact Alan Campbell at 202-551-4224 or Tim Buchmiller at 202-551-3635 with 
any other
questions.



                                                        Sincerely,

FirstName LastNameSizhen Wang                           Division of Corporation 
Finance
                                                        Office of Industrial 
Applications and
Comapany NameGenetron Holdings Limited
                                                        Services
October 27, 2022 Page 2
cc:       Xuelin Wang
FirstName LastName