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                           September 15, 2022

       Yusheng Han
       Chief Executive Officer
       Burning Rock Biotech Ltd
       No. 5 Xingdao Ring Road North
       International Bio Island
       Guangzhou, 510005 The People's Republic of China

                                                        Re: Burning Rock 
Biotech Ltd
                                                            Amendment No. 3 to 
Registration Statement on Form F-3
                                                            Filed September 12, 
2022
                                                            File No. 333-264577

       Dear Mr. Han:

              We have reviewed your amended registration statement and have the 
following
       comment. In our comment, we may ask you to provide us with information 
so we may better
       understand your disclosure.

              Please respond to this letter by amending your registration 
statement and providing the
       requested information. If you do not believe our comment applies to your 
facts and
       circumstances or do not believe an amendment is appropriate, please tell 
us why in your
       response.

              After reviewing any amendment to your registration statement and 
the information you
       provide in response to the comment, we may have additional comments. 
Unless we note
       otherwise, our references to prior comments are to comments in our 
August 30, 2022 letter.

       Amendment No. 3 to Registration Statement on Form F-3 filed September 
12, 2022

       Prospectus Summary, page 18

   1.                                                   We note your revised 
disclosure in response to prior comment 3 that discusses the
                                                        statement of protocol 
with the China Securities Regulatory Commission and the Ministry
                                                        of Finance of the 
People's Republic of China. Please revise to also discuss that the
                                                        PCAOB is required to 
reassess its determinations with regard to inspecting and
                                                        investigating in 
mainland China and Hong Kong by the end of 2022.
 Yusheng Han
Burning Rock Biotech Ltd
September 15, 2022
Page 2

      Please contact Christine Westbrook at 202-551-5019 or Celeste Murphy at 
202-551-
3257 with any questions.



                                                        Sincerely,
FirstName LastNameYusheng Han
                                                        Division of Corporation 
Finance
Comapany NameBurning Rock Biotech Ltd
                                                        Office of Life Sciences
September 15, 2022 Page 2
cc:       Shuang Zhao, Esq.
FirstName LastName