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 August 28, 2020




 Securities and Exchange Commission

 Division of Corporation Finance

 100 F Street, N.E.

 Washington, DC 20549



 NovaBay Pharmaceuticals, Inc. (the “Company”)

 Form S-3, File No. 333-248238

   Ladies and Gentlemen:


Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company hereby requests that the Securities and Exchange Commission (the “Commission”) take appropriate action to cause the above-referenced Registration Statement on Form S-3 to become effective as of 5:00 p.m. (Eastern time) on Tuesday, September 1, 2020, or as soon as practicable thereafter.




Very truly yours,


NovaBay Pharmaceuticals, Inc.



 /s/ Justin Hall 


Justin Hall


Chief Executive Officer and General Counsel



Abby E. Brown, Squire Patton Boggs (US) LLP