AILERON THERAPEUTICS, INC.

490 Arsenal Way, Suite 210

Watertown, MA 02472

August 19, 2020

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

 

Re:

Aileron Therapeutics, Inc.

Registration Statement on Form S-3

File No. 333-244367

Request for Acceleration

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Aileron Therapeutics, Inc. (the “Registrant”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-244637), so that it may become effective at 4:00 p.m. Eastern time on August 21, 2020, or as soon thereafter as practicable, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff.

 

Very truly yours,
AILERON THERAPEUTICS, INC.
By:  

/s/ Richard J. Wanstall

Name:   Richard J. Wanstall
Title:   Chief Financial Officer and Treasurer

 

cc:

Stuart M. Falber

Wilmer Cutler Pickering Hale and Dorr LLP