June 30, 2020

VIA EDGAR SUBMISSION

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, NE

Washington, DC 20549

Attention: Christopher Edwards

 

Re:

Trevi Therapeutics, Inc.

    

Registration Statement on Form S-3

    

File No. 333-239499

    

Request for Acceleration

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Trevi Therapeutics, Inc. hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-239499), so that it may become effective at 4:00 p.m., Eastern time, on July 2, 2020, or as soon as practicable thereafter.

 

Very truly yours,
By:   /s/ Jennifer Good
 

Jennifer Good

Chief Executive Officer